Vitamin D Receptor in Muscle Atrophy of Elderly Patients: A Key Element of Osteoporosis-Sarcopenia Connection
نویسندگان
چکیده
منابع مشابه
Vitamin D and Sarcopenia
Vitamin D is a fat-soluble vitamin, and has an essential role in calcium homeostasis and keeping of normal bone metabolism [5]. Data suggest that vitamin D status is crucial for the normal function of different organs, such as pancreatic β-cells, vascular endothelial cells, neurons, immune cells, osteoblasts, and myocytes, where vitamin D receptors are expressed [5]. In addition, vitamin D defi...
متن کاملVitamin D receptor genotype is associated with fat-free mass and sarcopenia in elderly men.
We investigated the association of vitamin D receptor (VDR) genotype with fat-free mass (FFM) in a cohort of 302 older (aged 58-93 years) Caucasian men who underwent body composition analysis by dual-energy X-ray absorptiometry, and completed questionnaires addressing comorbidities, physical activity, and dietary intake. All participants were genotyped for a VDR translation start site (FokI) po...
متن کاملStatus of Vitamin-D in diabetic patients
Abstract Background: Vitamin D (vit D) deficiency has been found to have an inverse relationship with the occurrence of type-2 diabetes mellitus (DM). The aim of this study was to assess the vit D level in type-2 diabetic patients. Methods: One hundred-twenty DM patients selected as case group and 120 healthy individuals as control group were investigated in this study from October 2011 to S...
متن کاملPrevalence of osteoporosis and vitamin D receptor gene polymor-phisms (FokI) in an Iranian general population based study (Kurdistan) (IMOS)
Background: Osteoporosis, or porous bone, is a disease characterized by low bone mass density (BMD) and structural deterioration of bone tissue, leading to bone fragility and increased risk of hip, spine, and wrist fractures. There are numerous risk factors for osteoporosis. While many of these factors are non-genetic in nature, there is a definite genetic component responsible for this condi...
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ژورنال
عنوان ژورنال: Aging and disease
سال: 2018
ISSN: 2152-5250
DOI: 10.14336/ad.2018.0215